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16 December 2016

The index of microvascular resistance measured acutely predicts infarct severity

and left ventricular function at 3 months in patients with STEMI

RJ McGeoch

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Summary

In STEMI patients in spite of 90 percent achieving TIMI3,  flow a significant proportion do not achieve complete myocardial perfusion. Microvascular obstruction can affect up to 50 percent of patients who undergo successful reperfusion. Microvascular obstruction in STEMI patients is associated with increased adverse clinical events. McGeoch and colleagues presents the results of a study they performed to measure the index of microcirculatory resistance(IMR) using the RADI pressure and temperature wire.This measured immediately after successful PCI used as a predictor of microvascular resistance and myocardial damage using ceCMR as gold standard

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Summary

In STEMI patients in spite of 90 percent achieving TIMI3,  flow a significant proportion do not achieve complete myocardial perfusion. Microvascular obstruction can affect up to 50 percent of patients who undergo successful reperfusion. Microvascular obstruction in STEMI patients is associated with increased adverse clinical events. McGeoch and colleagues presents the results of a study they performed to measure the index of microcirculatory resistance(IMR) using the RADI pressure and temperature wire.This measured immediately after successful PCI used as a predictor of microvascular resistance and myocardial damage using ceCMR as gold standard

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